Big Data in Organizations and the Role of Human Resource Management

Big data are changing the way we work. This book conveys a theoretical understanding of big data and the related interactions on a socio-technological level as well as on the organizational level. Big data challenge the human resource department to take a new role. An organization’s new competitive advantage is its employees augmented by big data

Typical local measurements in generalized probabilistic theories: emergence of quantum bipartite correlations

What singles out quantum mechanics as the fundamental theory of nature? Here we study local measurements in generalized probabilistic theories (GPTs) and investigate how observational limitations affect the production of correlations. We find that if only a subset of typical local measurements can be made then all the bipartite correlations produced in a GPT can be simulated to a high degree of accuracy by quantum mechanics. Our result makes use of a generalization of Dvoretzky’s theorem for GPTs. The tripartite correlations can go beyond those exhibited by quantum mechanics, however.What singles out quantum mechanics as the fundamental theory of nature? Here we study local measurements in generalized probabilistic theories (GPTs) and investigate how observational limitations affect the production of correlations. We find that if only a subset of typical local measurements can be made then all the bipartite correlations produced in a GPT can be simulated to a high degree of accuracy by quantum mechanics. Our result makes use of a generalization of Dvoretzky’s theorem for GPTs. The tripartite correlations can go beyond those exhibited by quantum mechanics, however

Typical local measurements in generalised probabilistic theories: emergence of quantum bipartite correlations

What singles out quantum mechanics as the fundamental theory of Nature? Here we study local measurements in generalised probabilistic theories (GPTs) and investigate how observational limitations affect the production of correlations. We find that if only a subset of typical local measurements can be made then all the bipartite correlations produced in a GPT can be simulated to a high degree of accuracy by quantum mechanics. Our result makes use of a generalisation of Dvoretzky's theorem for GPTs. The tripartite correlations can go beyond those exhibited by quantum mechanics, however.Comment: 5 pages, 1 figure v2: more details in the proof of the main resul

The joy of the easter egg and the pain of numb hands: the augmentation and limitation of reality through video games

Becoming immersed in a world where our perception of reality is highly mediated allows for the creation of an audiovisual lexicon that expands over many platforms and times. In this context we might observe the case of video games which, as a medium, does not limit themselves to the creation of puzzles to be solved, to pretend participation in the Rock and Roll world, or lead us to unexpected damages to our "flesh". Games allow us different levels of enjoyment and also lead us to discover the physical limits of our bodies within the expansion of our senses. Furthermore, hidden in many of these games we discover many hints, influences, remnants, appropriations and quotes, expanding the web of signs and significations far beyond the limits of the games themselves. However, the extent and consequences of video games as entertainment and communicational devices surpasses their potential for representation and signification, and even impact aspects of our lives such as our physiognomy and psychology-we experience carpal tunnel syndrome, addiction and withdrawal symptoms, and we delve in debates that isolate us or make us only socially able within the confines of virtual worlds. All in all, video games have become part and parcel of our existence, extensions of our perspectives of the world that surround us. Games shape our rational cognition, they build upon our new relational memories, but they also show the limitations of our physical rootedness. This article hopes to elicit an exploration into the reality of the media and mediatized reality of our physical limitations

Die Idee dahinter ... : Aspekte zur Gestaltung lernreicher Lehre

Der Band umfasst zahlreiche Beispiele von Lehrenden, die ihre Veranstaltungen in mehreren Aspekten ‚lernreich(er)’ gestaltet haben. Die Konzepte wurden alle im Rahmen des Vertiefungsmoduls des Programms „Professionelle Lehrkompetenz für die Hochschule“ des Netzwerks "hochschuldidaktik nrw" an der Universität Siegen entwickelt oder weiterentwickelt. Die elf Beiträge umfassen ein breites Spektrum an Veranstaltungsformaten und Fächern: Natur- und Ingenieurwissenschaften sind ebenso vertreten wie Architektur, Pädagogik, Soziale Arbeit und Literaturwissenschaft. Bei den Veranstaltungen handelt es sich um Praktika, Seminare, Übungen usw., oft mit Projektcharakter bzw. -elementen, häufig auch mit wechselnden Lernorten, semester-begleitend oder kompakt

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

Peer reviewedPublisher PD

Sustainable Innovation in a Multi-University Master Course

Mobility, multi-locality, and transnational migration are current social developments among the population of the European Union. These social developments in society and companies, linked to the challenges of sustainability, lead to new requirements for working in the European Union. Teaching and learning in higher education needs to adapt to these requirements. As a result, new and innovative teaching and learning practices in higher education should provide competencies for transnational teamwork in the curriculum of tomorrow's engineers in order to ensure their competitiveness in the job market and advantage in their future careers. Thirteen European students from four countries participated in a new project-based course, called the "European Engineering Team". Students focused on the development of two innovative and sustainable products. The goal of this paper is to present the thermal pallet cover, which is the result of the first one-year transnational and sustainability-oriented project. This paper also aims to present the process of performing the project. It provides the overview and discussion of engineering and management tasks that students completed in the transnational environment, working remotely at their own campuses between scheduled transnational meetings. The work contributes to project-oriented learning that may constitute a basis for teaching holistic engineering courses at mechanical and industrial engineering departments

Neuronal hypoxia in vitro: Investigation of therapeutic principles of HUCB-MNC and CD133+ stem cells

Background The therapeutic capacity of human umbilical cord blood mononuclear cells (HUCB-MNC) and stem cells derived thereof is documented in animal models of focal cerebral ischemia, while mechanisms behind the reduction of lesion size and the observed improvement of behavioral skills still remain poorly understood. Methods A human in vitro model of neuronal hypoxia was used to address the impact of total HUCB-MNC (tMNC), a stem cell enriched fraction (CD133+, 97.38% CD133-positive cells) and a stem cell depleted fraction (CD133-, 0.06% CD133-positive cells) of HUCB-MNC by either direct or indirect co-cultivation with post-hypoxic neuronal cells (differentiated SH-SY5Y). Over three days, development of apoptosis and necrosis of neuronal cells, chemotaxis of MNC and production of chemokines (CCL2, CCL3, CCL5, CXCL8, CXCL9) and growth factors (G-CSF, GM-CSF, VEGF, bFGF) were analyzed using fluorescence microscopy, FACS and cytometric bead array. Results tMNC, CD133+ and surprisingly CD133- reduced neuronal apoptosis in direct co-cultivations significantly to levels in the range of normoxic controls (7% ± 3%). Untreated post-hypoxic control cultures showed apoptosis rates of 85% ± 11%. tMNC actively migrated towards injured neuronal cells. Both co-cultivation types using tMNC or CD133- reduced apoptosis comparably. CD133- produced high concentrations of CCL3 and neuroprotective G-CSF within indirect co-cultures. Soluble factors produced by CD133+ cells were not detectable in direct co-cultures. Conclusion Our data show that heterogeneous tMNC and even CD133-depleted fractions have the capability not only to reduce apoptosis in neuronal cells but also to trigger the retaining of neuronal phenotypes

Prospective Environmental Life Cycle Assessment of Nanosilver T-Shirts

A cradle-to-grave life cycle assessment (LCA) is performed to compare nanosilver T-shirts with conventional T-shirts with and without biocidal treatment. For nanosilver production and textile incorporation, we investigate two processes: flame spray pyrolysis (FSP) and plasma polymerization with silver co-sputtering (PlaSpu). Prospective environmental impacts due to increased nanosilver T-shirt commercialization are estimated with six scenarios. Results show significant differences in environmental burdens between nanoparticle production technologies: The "cradle-to-gate" climate footprint of the production of a nanosilver T-shirt is 2.70 kg of CO2-equiv (FSP) and 7.67-166 kg of CO2-equiv (PlaSpu, varying maturity stages). Production of conventional T-shirts with and without the biocide triclosan has emissions of 2.55 kg of CO2-equiv (contribution from triclosan insignificant). Consumer behavior considerably affects the environmental impacts during the use phase. Lower washing frequencies can compensate for the increased climate footprint of FSP nanosilver T-shirt production. The toxic releases from washing and disposal in the life cycle of T-shirts appear to be of minor relevance. By contrast, the production phase may be rather significant due to toxic silver emissions at the mining site if high silver quantities are require